Category: Science

Red Vein Kratom: The Complete Guide

This article contains a complete guide to Red Vein Kratom, including what defines it, how it is different from other strains, and its general effects. The Many Theories About What Defines Red Vein Kratom One of the most common questions that people ask is what defines Red Vein Kratom, or in other words, what’s the difference between Red Vein and the other strains? There are actually numerous theories about what defines Kratom as Red Vein. One of the earliest theories I heard was that the strain colors match the colors on the stoplight, with red meaning stop and green...

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How Long Does Kratom Last? Roughly 4-8 hours

A common question that new Kratom users often ask is how long does Kratom last? This article gives a thorough answer to this question based on empirical and subjective data. Scientifically, how long the effects of a substance lasts depends on the half-life, which is the amount of time it takes for half of the concentration of a substance to be eliminated from the body. Short acting substances have short half-lives, whereas long acting substances have long half-lives. According to scientific studies, Kratom’s primary alkaloid Mitragynine has a half-life of approximately 3.85 hours. The half-life of Kratom as a...

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Can You Overdose On Kratom? The Answer Is No

A common question that people ask is can you overdose on Kratom? This question is especially common since the FDA has waged a misinformation war against Kratom, basically saying that Kratom is deadly since it has opioid effects. However, as will be shown in this article, science definitively proves that it is not possible to truly overdose on Kratom. The primary reason that Kratom cannot cause overdoses is that it does not recruit beta-arrestin-2. Essentially, beta-arrestin-2 is an intracellular protein which suppresses the body’s norepinephrine, i.e. adrenaline, and this suppression of norepinephrine is what causes the lungs to shutdown...

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Kratom Does Not Cause Drug Effects In The Mesolimbic Pathway, Explaining Why Kratom Lacks Addiction Potential

It is subjectively well known that Kratom addiction is not even comparable to the intense addiction caused by synthetic opioids and opiates. Whereas users of synthetic opioids and opiates have a tendency to take as much of the drugs as possible as often as possible while chasing a high, Kratom users usually take Kratom once or twice a day and are satisfied. Another way of saying it is that whereas synthetic opioid and opiate users are constantly thinking about their next fix, Kratom users usually do not think about their next Kratom dose, especially if they’ve already taken it...

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What Is Kratom?

I’ve written hundreds of articles about Kratom, but I’ve realized that I have not written an article which answers the simple question, what is Kratom? Although this question is simple, it is critically important, since whenever someone finds out about Kratom for the first time, this question is the first thing they ask, and the answer they receive to this question can permanently influence their opinion about Kratom. Kratom is a leaf from the Mitragyna Speciosa tree, a tree which grows indigenously in Southeast Asia, primarily in Indonesia, Malaysia, Vietnam, and Thailand. In these regions Kratom has been used...

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The CDC Is Requesting Public Comments In Order To Update Their Guidelines For Prescribing Opioids, And It Would Be Good For Kratom Users To Comment

The Centers for Disease Control and Prevention (CDC) is planning on updating and expanding the CDC Guideline for Prescribing Opioids for Chronic Pain, and is asking for public comments in order to help with the process. Further, these public comments are being published permanently in the public record on Regulations.gov. Specifically, the CDC is looking for experiences and perspectives on the benefits and harms of opioid use, how effective opioid pain treatment is in general, as well as experiences regarding opioid addiction and overdose resulting from chronic pain treatment. This is highly relevant to the Kratom community, which is...

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The Opioid Pandemic Has Killed 500,000 People In The United States Since 1999, And Data Shows That It Is Getting Worse Every Year

According to data from the Centers for Disease Control (CDC), 446,000 people have died from opioid overdoses between 1999 and 2018. Extrapolating and adding in 2019, where there were probably around 50,000 opioid overdose deaths, brings the Opioid Pandemic death toll in the United States since 1999 to 500,000. Further, the Opioid Pandemic in the United States is consistently getting worse. In 1999 there were 8,000 opioid overdoses. In 2002 it spiked to 12,000 opioid overdoses. By 2009 the number of opioid overdoses exceeded 20,000, and by 2015 it jumped to 33,000, before hitting the 2017-2018 levels of 47,000...

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Big Pharma Is Projecting That The Opioid Pandemic Will Become Much Worse, And Using These Projections To Attract Investments

Big Pharma runs the Opioid Pandemic like a business, and just like any other business, they issue market reports showing the state of the market and projections for growth in order to attract investment. This article reveals the pure greed and evil that comprises the backbone of Big Pharma. Specifically, there is a market report titled ‘Opioid Use Disorder Market Worth $4.5 Billion by 2026 | CAGR: 10.1%: Grand View Research, Inc.’ which was broadcast over the global PRNewswire, just like other corporate announcements and market reports. When it comes down to it, this report is saying that the...

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A Guide To The Dozens Of Alkaloids In Kratom, And The Benefits Of Each Of Them

The Kratom alkaloids Mitragynine and 7-hydroxymitragynine are the most well known, since they are the alkaloids which are primarily responsible for Kratom’s opioid effects. However, Kratom actually has dozens of other alkaloids, in-fact over 40 different alkaloids according to a scientific study, and this article describes the benefits and properties of each of them. Mitragynine and 7-Hydroxymitragynine Before diving into the other Kratom alkaloids, it is important to note that Mitragynine and 7-hydroxymitragynine have numerous beneficial properties including being analgesic (painkilling), antitussive (cough suppressing), anti-diarrheal, and antimalarial. Also notably, Mitragynine accounts for 66% of the total alkaloid content of...

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Kratom Contains Natural Opioid Antagonists, Which Is Likely The Scientific Reason That Kratom Is So Safe

Kratom veterans often use the phrase ‘less is more’ regarding Kratom dosages. This basically means that Kratom has a maximum optimal dose, and beyond that dose Kratom has no further positive effects. This helps to decrease Kratom tolerance, as opposed to synthetic opioids and opiates which can be dosed more and more, leading to severe addiction. Also, in general Kratom users can take the same dose every day long term without having to increase it, unlike synthetic opioids and opiates where the dose has to constantly be increased, and eventually synthetic opioids and opiates stop working no matter how...

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A Variety Of Medicinal Herbs Can Potentiate Kratom’s Effects, Including Kava, Valerian, Chamomile, Passionflower, And Skullcap

There has been plenty of talk on the internet throughout the years about how to potentiate the effects of Kratom in order to achieve a more relaxing and stronger experience. Some people suggest taking synthetic OTC medicines, but I am a believer that natural medicinal herbs are the best potentiators for Kratom. Usually Kratom by itself is strong enough for me, but if I ever want to achieve extreme relaxation I’ll drink a cup of Yogi Kava tea or Yogi sleepy time tea, and sometimes even mix them together. In the below image is a list of the ingredients....

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Kratom Can Provide Relief From Coronavirus Symptoms, And It Has Antiviral And Immunostimulant Properties

The Coronavirus is the biggest news of this year, and its changing life as we know it at least temporarily, with schools, sports leagues, public events, and many workplaces closing down. The reason that the government is taking these measures to stop the spread of the virus is to ‘flatten the curve’. This basically means that the government is resigned to the fact that the Coronavirus will completely spread, but wants the cases to come in slower so hospitals and emergency services aren’t overwhelmed. This is because there is no vaccine for the Coronavirus, and if a vaccine is...

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