Category: Science

Kratom Is An Excellent Anti-Anxiety Alternative: Scientific Study Confirms Kratom Has Anxiolytic Effects On Par With Diazepam, And Kratom Is Magnitudes Safer Than Benzodiazipines

Anxiety is a prevalent phenomena in our society, and unfortunately the primary drug that doctors prescribe for anxiety is Benzodiazepines. Although Benzodiazepines do get rid of anxiety temporarily, that temporary relief comes at an extreme price. First off, if Benzodiazepines are used long term then an extreme physical addiction arises, an addiction so powerful that people have died from the withdrawals. Indeed, this makes Benzodiazepines even more dangerous than synthetic opioids and opiates, since at the least opioid withdrawal symptoms generally do not cause death. Further, Benzodiazepine addiction comes with a rapidly increasing tolerance, and users will take more...

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Scientific Study Finds That Kratom Has Little To No Addiction Liability, And That Kratom Is No More Addictive Than Salt Water, In Addition To Finding That Kratom Decreases Heroin Addiction

Back in 2016 the DEA was about to declare Kratom a Schedule I illegal drug, with Schedule I being any drug that is highly abusable and has no recognized therapeutic value. Fortunately the DEA did not make Kratom illegal, but that incident inspired a group of scientists to determine whether Kratom really was an abusable drug, via the scientific study ‘Abuse liability of mitragynine assessed with a self-administration procedure in rats’. Incredibly, it was empirically determined that Kratom has no more abuse potential than salt water, and that Kratom has a high therapeutic potential, as will be explained in...

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There Are Other Primary Alkaloids In Kratom Besides Mitragynine And 7-Hydroxymitragynine, Including Speciogynine, Paynantheine, Speciociliatine, And Corynoxine B, And They Have Important Effects And Benefits

It is common knowledge that the most potent opioid alkaloids in Kratom are 7-hydroxymitragynine and Mitragynine, and usually customers who are researching Kratom products only look at the concentrations for these two alkaloids. In-fact, lab tests almost never test for any other alkaloids in Kratom besides Mitragynine and 7-hydroxymitragynine. However, Kratom actually has around 50 alkaloids, with new alkaloids being discovered all the time. Further, some of these other alkaloids are abundant enough to be considered primary alkaloids, and these lesser known primary alkaloids play a critical role in Kratom’s pharmacology and medicinal benefits. The below chart from the...

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Scientific Study Finds That 7-Hydroxymitragynine Is Approximately 50X More Potent Than Mitragynine, And Therefore 7-Hydroxymitragynine Is Responsible For Most of Kratom’s Effects

The primary alkaloid by far in Kratom leaf is Mitragynine, and indeed Kratom products are typically rated by how much Mitragynine they contain. However, Kratom has dozens of other alkaloids, all of which play an important role in Kratom’s effects, and one of the most important of these alkaloids is 7-hydroxymitragynine, despite the fact that 7-hydroxymitragynine is found in very low concentrations in Kratom leaf. In general potent and fresh Kratom has 1-1.5% Mitragynine. Indeed, even very strong Kratom can have just 1% Mitragynine, meaning there is 10 milligrams of Mitragynine per gram. On the other hand, 7-hydroxymitragynine is...

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Scientists Find That Kratom Alleviates The Symptoms Of Psychosis, Making Kratom An Excellent Alternative To The Current Regimen Of Psychosis Meds Which Have Highly Negative Side-Effects

It is already well-known among Kratom users that Kratom is an excellent supplement for mental health. Indeed, some real-life stories about how Kratom helped people with depression, stress, anxiety, bipolar, and PTSD can be read at this link. Apparently psychosis is yet another mental health order that can be treated with Kratom according to a scientific study. Specifically, a scientific study from the University of Malaya titled ‘Mitragyna speciosa Leaf Extract Exhibits Antipsychotic-Like Effect with the Potential to Alleviate Positive and Negative Symptoms of Psychosis in Mice’ has found that Kratom alleviates the symptoms of psychosis, and that in general...

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There Are Several Plants Closely Related To Kratom In The Mitragyna Genus, And They All Have Medicinal Properties

Kratom (Mitragyna Speciosa) is incredibly popular worldwide, and especially in the United States, due to its pain relieving and stress relieving properties. However, most Kratom users are probably not aware that Kratom is not alone, and that there are several other plants which are closely related to Kratom, and that these plants have their own unique medicinal properties and are perhaps worth looking into as will be explained in this article. Specifically, Kratom is in the Mitragyna Genus, with a Genus being a group of species that are closely related. Species in the Mitragyna Genus include Kratom (Mitragyna Speciosa),...

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Scientists Determine That Kratom’s Effects Come In Two Waves, With Mitragynine Peaking At 30 Minutes And 7-Hydroxymitragynine Peaking At 100 Minutes

A new scientific study titled ‘Pharmacokinetics and Safety of Mitragynine in Beagle Dogs’ has dived deep into Kratom’s pharmacokinetics, and has empirically confirmed that Kratom’s effects come in two waves. In this study Kratom was given orally to dogs, and this is the first time that Kratom pharmacokinetics have been assessed for a non-rodent animal. Of course a human study would yield more accurate results, but the data from this study is certainly more accurate than other studies which use mice and rats as their test subjects. On a side note, the scientists say the dogs didn’t have any...

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Mitraphylline, An Alkaloid Found In Kratom, Has Anti-Cancer Properties According To Multiple Scientific Studies

Kratom has a long list of health benefits, and perhaps one of those benefits is anti-cancer properties thanks to the alkaloid Mitraphylline. Before anyone torches me for writing that Kratom may have anti-cancer properties, please read the article below, since this theory is based on multiple peer-reviewed scientific studies. First off, a notable thing about Mitraphylline is that it is found in both Kratom and Cat’s Claw (Uncaria Tomentosa). There are plenty of other examples in nature of the same alkaloids being found in completely different plants, and it is likely because these plants have a common evolutionary ancestor....

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Scientific Study Confirms That Kratom Increases Pain Tolerance, I.e. Provides Pain Relief

A new scientific study titled ‘Kratom and Pain Tolerance: A Randomized, Placebo-Controlled, Double-Blind Study’ has been published by the University Sains Malaysia and the Yale School of Medicine, and it provides solid empirical proof that Kratom has pain relieving effects. 26 people participated in this experiment, and throughout a 1 day period participants were given a random sequence of Kratom or a placebo, and since it was a double-blind study the patients didn’t know which one they were receiving. In order to measure tolerance to pain, patients stuck their hand in an ice bath, and the time was measured...

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Scientists Discover 4 New Kratom Alkaloids

A previous article on Kratom Cafe discussed how Kratom has roughly 40 alkaloids, but also mentions “Further, it seems that every year more Kratom alkaloids are being discovered, so the almost 40 alkaloids referenced in this article may not be all of the Kratom alkaloids.” Indeed, scientists have just discovered 4 new Kratom alkaloids, and it is likely that new alkaloids will continue to be discovered as Kratom science advances. Specifically, the new alkaloids discovered are epiallo-isopaynantheine, epiallo-isopaynantheine-N(4)-oxide,  3-epirhynchophylline, and 3-epicorynoxine B. These alkaloids are related to the already known alkaloids, but have a slightly different structure and are...

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How To Make Extremely Potent Kratom Extract With Common Household Supplies

If you want a stronger Kratom experience, and want something beyond the effects of regular powder, then read this article. Below I describe how to make an extremely potent Kratom extract with common household supplies. Literally, you probably have everything you need to make this potent extract already in your kitchen. The reason I made this extract is because lately I’ve been taking Kratom capsules, and I need to take around 20 capsules (10 grams) to get the Kratom experience that I want. This is just too many capsules, so I usually only take 15 and I end up...

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Tea, Chocolate, Tomatoes, And Cabbages Often Have Much Higher Heavy Metal Concentrations Than Kratom, And Heavy Metals Are In All Plant-Based Foods Since All Soil Contains It

The Food and Drug Administration (FDA) incited public hysteria in 2018 when they said that Kratom contained high concentrations of heavy metals, specifically Lead and Nickel. What the FDA intentionally didn’t measure however is that all plant-based foods, and in-fact practically all foods, contain heavy metals since heavy metals naturally occur in all of the soil on Earth. Indeed, tea, chocolate, tomatoes, and cabbages often contain higher heavy metal concentrations than Kratom, as will be proven below. First off, heavy metals are ubiquitous in Earth’s soil. A study which aggregated agricultural and homeowner soil tests found that soil typically...

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